On Attaining Maximal and Durable Suppression of the Viral Load

Steady state and transient response analysis for an HIV/AIDS model will be conducted in order to determine the extent to which the viral load is suppressible. Results indicate that viral dynamics, before and after the initiation of therapy, are oscillatory, and as such, the viral load will transiently oscillate before settling to some on treatment steady state. Conditions that are conducive to the attainment of “maximal and durable suppression of viral load” will be outlined. This study also provides some insight on the issue of recurrent viral load blips. The effect of treatment when initialized at various stages of the infection progression will be demonstrated.